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. 2016 Mar 29;11(3):e0152300. doi: 10.1371/journal.pone.0152300

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© 2016 Wang et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — Representative micrographs show the expression of MAP4K5 in normal pancreatic tissue (A) and chronic pancreatitis (B). The benign pancreatic ductal cells in normal pancreas and chronic pancreatitis show strong cytoplasmic staining for MAP4K5. The adjacent pancreatic acinar cells and pancreatic islet cells are either negative or have very low expression of MAP4K5. C & D, Representative micrographs show the loss of MAP4K5 expression in two different pancreatic ductal adenocarcinoma samples. Strong cytoplasmic staining for MAP4K5 in benign pancreatic ductal cells in the left upper corner in D served as internal positive control. Original magnifications: 200X.