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. 2016 Mar 29;11(3):e0152488. doi: 10.1371/journal.pone.0152488

Table 3. Univariate and multivariate adjusted hazard ratios for all-cause and cardiovascular mortality in patients.

All patients Male patients Female patients
All-cause CVD All-cause CVD All-cause CVD
HR 95% CI p HR 95% CI p HR 95% CI p HR 95% CI p HR 95% CI p HR 95% CI p
Unadjusted 0.041 0.007, 0.233 < 0.001 0.007 0.001, 0.081 < 0.001 0.044 0.004, 0.527 0.014 0 0.000, 0.106 0.004 0.03 0.002, 0.393 0.007 0.009 0.000, 0.191 0.003
Model 1 0.075 0.014, 0.421 0.003 0.01 0.001, 0.131 < 0.001 0.066 0.006, 0.759 0.029 0.001 0.000, 0.132 0.001 0.083 0.007, 0.980 0.048 0.033 0.002, 0.657 0.026
Model 2 0.058 0.010, 0.338 0.002 0.013 0.001, 0.155 < 0.001 0.016 0.001, 0.272 0.004 0 0.000, 0.045 0.004 0.094 0.008, 1.164 0.066 0.048 0.002, 0.994 0.05
Model 3 0.075 0.010, 0.552 0.011 0.003 0.000, 0.055 < 0.001 0.052 0.002, 1.363 0.076 0 0.000, 1.013 0.05 0.04 0.002, 0.968 0.048 0.004 0.000, 0.216 0.007

Abbreviations: CVD- cardiovascular disease, HR- hazard ratio, CI- confidence interval

Model 1 was adjusted for age and gender. Model 2 was adjusted for Model 1+ DM, MAP, urine output, Net UF, rGFR, creatinine clearance and sodium. Model 3 was adjusted for Model 2+malnutrition (body mass index, serum albumin, hemoglobin level and TC, TG) and mineral and bone disorder-related factors (levels of serum calcium, phosphate, intact parathyroid hormone, prescription of Calcium carbonate, active vitamin D analogue).