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. 2016 Mar 29;11(3):e0151815. doi: 10.1371/journal.pone.0151815

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© 2016 Li et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) MMP9 expression was correlated with glioma grade (p<0.001). Glioma of grade IV showed a significantly increased in MMP9 expression compared to grade II and III gliomas (p<0.0001, p<0.0001, respectively). MMP9 expression level in grade III gliomas was markedly higher than that in grade II gliomas (p<0.0001). (B, C) Likelihood ratio test showed that MMP9 was significantly associated with tumor grade in two independent glioma dataset (p<0.001, p<0.001, respectively) * p< 0.05; **** p<0.0001.