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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Immunol Methods. 2015 Nov 1;427:105–116. doi: 10.1016/j.jim.2015.10.009

Figure 3. Heat map of the minimal sequence difference of each human germline VH gene pair [12] at full sequence length.

Figure 3

Minimal nucleotide differences among all alleles pairs between genes. Distances range from 0 (black) through red (100) and yellow (200) to white (>200). The comparison begins at the 3' end of each full-length VH gene. The blue numbers in the circles represent the numbers of mismatched nucleotides in the most similar pairs. These pairs of VH genes cannot be discriminated from each other at almost any length or mutation frequency.