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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Immunol Methods. 2015 Nov 1;427:105–116. doi: 10.1016/j.jim.2015.10.009

Figure 7. Phylogenetic tree of a clone from a plasmablast dataset of a lupus patient.

Figure 7

Each circle represents a sequence. Different colors and tags show what V gene the sequences were originally identified. The germline was made by (A) filling in IGHV3-11*01 germline sequence, (B) filling in IGHV3-48*01 germline sequence or (C) ignoring the different positions of these V genes. The mutations of each hypothetical and real node are shown. The additional mutations in (A) and (B) compared to (C) are shown in red.