Table 4.
Targeting ligands in PDT
| Class | Ligand | Target | PS | Application | Reference |
|---|---|---|---|---|---|
| Monoclonal antibody | OC125 | Ovarian cancer | Chlorin(e6) | Cancer, in vitro, in vivo | [157] |
| Peptide | Octreotide | Somatostatin receptor | Chlorin(e6) | Leukaemia, in vitro | [81] |
| Peptide | RGD tripeptide | αvβ3 integrin | Phaeophorbide a | Cancer, in vitro | [76] |
| Lipoprotein | Low-density lipoprotein | LDL receptor | Tetra-t-butyl silicon phthalocyanine | Cancer, atherosclerosis, in vitro, in vivo | [158] |
| Serum protein | Transferrin | Transferrin receptor | Hematoporphyrin | Cancer, in vitro | [77] |
| Serum protein | Modified albumin | Scavenger receptor | Chlorin(e6) | Atherosclerosis, in vitro, in vivo | [159] |
| Vitamin | Folic acid | Folate receptor | Phaeophorbide a | Cancer, in vitro | [76] |
| Steroid | Oestradiol | Steroid receptor | Phaeophorbide a | Breast cancer, in vitro | [160] |
| Carbohydrate | Mannose | Mannose receptor | Meso-tetraphenylporphyrin | Cancer, in vitro | [161] |