. Author manuscript; available in PMC: 2017 May 15.

Published in final edited form as: Toxicol Appl Pharmacol. 2016 Feb 6;299:41–46. doi: 10.1016/j.taap.2016.02.004

Table 3.

Calculated deposition probability of a same sized NP aerosol like our 20 nm ¹⁹²IrNP aerosol in the respiratory tract of rats according to the Multiple Path Particle Deposition (MPPD) software either during nose-only inhalation or during intratracheal inhalation. The modelling parameters used are given in Table DB3 of Supplementary Material for both inhalation exposures.

Regions of respiratory tract	Nose-only inhalation	Intratracheal inhalation	Nose-only inhalation	Intratracheal inhalation
Deposition relative to	Inhaled ¹⁹²IrNP	Inhaled ¹⁹²IrNP	Deposited ¹⁹²IrNP	Deposited ¹⁹²IrNP
Total	0.439	0.666	1	1
Head	0.095	–	0.206	–
Trachea-bronchial	0.077	0.208	0.175	0.313