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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Liver Transpl. 2016 Apr;22(4):536–546. doi: 10.1002/lt.24394

Figure 2.

Figure 2

Profound depletion of interstitial (periportal) CD11c+ conventional myeloid (m)DC following diptheria toxoid (DT) administration in (A) the liver of a B6 CD11c-DTR mouse and (B) the liver of a chimeric B6 mouse in which only the hematopoietic cells were CD11c-DTR. (C) Survival of liver allografts from mDC-depleted B6 CD11c-DTR donor mice or from mDC-depleted B6 donor mice (CD11c-DTR chimeras) in which only the hematopoietic cells were CD11c+-DTR. Recipients were wild-type C3H mice. Experiments were conducted under an Institutional Animal Care and Use Committee-approved protocol (#130590681).