Figure 3. MYXV activates both intrinsic and extrinsic apoptosis.
Human U266 MM cells were either mock-treated or infected with MYXV at an MOI=10. 24 hours post-infection, cells were harvested and samples were separated on a SDS-PAGE gel. The presence and cleavage status of the initiator caspases Casp-2, Casp-8, Casp-9, and Casp-10 was determined using immunoblot.