Table 3.
FHPa vs all FHNb | FHPa vs FHNc with no 1st or 2nd degree | |||||
---|---|---|---|---|---|---|
FHP | FHN | Q valued | FHP | FHN | Q valued | |
Positive drug effects factore | −0.05 (0.110) | 0.07 (0.065) | 0.313 | −0.06 (0.118) | 0.19 (0.097) | 0.115 |
Negative drug effects factore | 0.25 (0.108) | −0.02 (0.064) | 0.038 | 0.26 (0.104) | −0.1 (0.086) | 0.010 |
Subjects classified as family history positive (FHP) had at least one 1st degree family member with AUD.
Subjects classified as family history negative (FHN) had no 1st degree family members with AUD. May have had 2nd degree relatives with AUD.
Subjects classified as FHN had no 1st or 2nd degree family members with AUD.
Adaptive Holm procedure (Q) was used to correct the p values for multiple comparisons.
Analyses adjusted for sex and binge drinking.