Figure 3. Expression of pro-inflammatory cytokines and chemokines in Stat4-/-Apoe-/- and Apoe-/- mice on western diet.
Cytokine gene expression was measured in visceral (A) and peri-aortic (B) adipose tissue using real-time PCR; results are expressed as fold change in gene expression in Apoe-/- mice compared to Stat4-/-Apoe-/- group and represent mean±SEM of n=8 mice/group; Chemokine expression in peri-aortic adipose tissue (C) was also measured by real-time PCR in n=6 mice /group; * = significantly different (p<0.05) compared to Stat4-/-Apoe-/- group.