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. 2016 Mar 8;5:e12509. doi: 10.7554/eLife.12509

Author response table 1.

Comparison of this study and Shi et al. study of the exosome complex.

DOI: http://dx.doi.org/10.7554/eLife.12509.093

Leiker

DSS (Shi et al.)

filtering criteria

FDR < 0.05

FDR < 0.05,

E-value < 0.00001, spectral count ≥ 3

FDR < 0.05,

manual inspection

#total cross-links

625

195

211

#inter-subunit cross-links

362

43

79

#intra-subunit cross-links

263

152

132

amount of sample

40 μg

15 μg

#proteins in the sample

740 (FDR 0.1%)

44 (FDR ~1%)

sample purity

poor

good

type of exosome

cytosolic exosome

(in the Rrp6 deletion background)

cytosolic exosome

and nuclear exosome

database for pLink search

740 proteins

17 proteins