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Schematic illustration of information flow through the direct pathway in cortical-basal ganglia-thalamocortical circuits. Information from the motor cortex passes to the dorsal striatum, globus pallidus, ventral lateral thalamus, and back to the motor cortex (red line). Information from the anterior cingulate and the prefrontal cortex passes to the ventral striatum, ventral pallidum, mediodorsal thalamus, and back to the anterior cingulate and prefrontal cortex (blue line).
