Table 3.
AROC and specificity at >90% sensitivity for RNFL parameters for comparing normal and glaucoma groups.
Comparison groups |
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---|---|---|---|---|---|---|---|---|---|
Normal-POAG |
Normal-NTG |
NTG-POAG |
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AROC | p1 | Sn/Sp | AROC | p2 | Sn/Sp | AROC | p3 | Sn/Sp | |
Superior RNFL thickness | 0.989 | <0.001 | 100/90 | 0.940 | <0.001 | 90/90 | 0.811 | <0.001 | 62/90 |
Inferior RNFL thickness | 0.999 | <0.001 | 100/90 | 0.876 | <0.001 | 69/90 | 0.917 | <0.001 | 80/90 |
Average RNFL thickness | 1.000 | <0.001 | 100/100 | 0.979 | <0.001 | 93/90 | 0.900 | <0.001 | 76/90 |
Inferior/superior RNFL thickness differencea | 0.644 | .061 | 37/90 | 0.626 | .091 | 30/90 | 0.533 | .662 | 13/90 |
Superior macular thickness | 0.997 | <0.001 | 100/90 | 0.889 | <0.001 | 67/92 | 0.854 | <0.001 | 53/90 |
Inferior macular thickness | 0.999 | <0.001 | 100/90 | 0.878 | <0.001 | 80/90 | 0.911 | <0.001 | 67/90 |
Inferior/superior macular thickness differenceb | 0.882 | <0.001 | 80/93 | 0.893 | <0.001 | 68/90 | 0.818 | <0.001 | 71/90 |
Total macular thickness | 0.972 | <0.001 | 100/90 | 0.872 | <0.001 | 73/90 | 0.894 | <0.001 | 66/90 |
p1, p value for normal-POAG comparison group; p2, p value for normal-NTG comparison group; p3, p value for NTG-POAG comparison group
POAG – primary open-angle glaucoma; NTG – normal tension glaucoma.
Absolute difference between superior and inferior RNFL thickness.
Absolute difference between superior and inferior macular thickness.