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. 2016 Mar 9;11(4):2806–2814. doi: 10.3892/ol.2016.4319

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — Inhibition of YAP expression suppresses angiogenesis in orthotopic implantation gastric cancer. CD31 staining images in (A) CON group, (B) NC group and (C) YAP-shRNA group (all magnification, x200). (D) Reverse transcription-polymerase chain reaction analysis of VEGF and FGF-2 messenger RNA level. (E) Mean number of blood vessels identified through CD31 staining. (F) Western blot analysis of VEGF and FGF-2 protein level and (G) quantification of the western blot. Data are presented as the mean ± standard deviation. **P<0.01 vs. CON and NC groups. CON, untransfected cells; NC, negative control vector-transfected cells; YAP-shRNA, yes-associated protein small hairpin RNA vector-transfected cells; VEGF, vascular endothelial growth factor; FGF-2, fibroblast growth factor 2; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.