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. 2016 Mar 30;36(13):3709–3721. doi: 10.1523/JNEUROSCI.3906-15.2016

Figure 6.

Figure 6.

Reduction of glial, but not neuronal, AdK slows SWA decay during an SWS episode and induces increased SWS consolidation. A, B, Tam-treated mice have a significantly slowed decay rate (τ = 22.5 min) compared with Veh-treated mice (τ = 8.6 min). C, Cumulative distribution of SWS episode durations is shifted to the right (more consolidated) in Tam-treated fAdK;GFAP:CreERVeh-treated mice. D, E, The time constant of SWA decay between control fAdK_Tam and neuronal AdK knock-out animals, fAdK;CaMKII:Cre (τ = 11.1 vs 10.1 min) was similar. F, Mice lacking neuronal AdK (fAdK;CaMKII:Cre) have a similar SWS episode duration distribution as fAdK_Tam mice.