Table III.
Receiver-operator characteristic (ROC) analysis for the prediction of rectal cancer using DCE-MRI.
| Radiologist 1 | Radiologist 2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Variables | Ktrans (min−1) | Kep (min−1) | Ve (%) | iAUC | Ktrans (min−1) | Kep (min−1) | Ve (%) | iAUC | |
| Cut-off | 0.156 | 0.549 | 0.354 | 24.183 | 0.156 | 0.52 | 0.372 | 23.41 | |
| Sensitivity | 100.00% | 60.00% | 92.50% | 92.50% | 100.00% | 65.00% | 85.00% | 92.50% | |
| Specificity | 93.30% | 86.70% | 60.00% | 93.30% | 93.30% | 86.70% | 66.70% | 100.00% | |
| AUC | 0.987 | 0.747 | 0.758 | 0.975 | 0.99 | 0.777 | 0.735 | 0.978 | |
| (95% CI) | (0.959–1.014) | (0.611–0.882) | (0.579–0.938) | (0.940–1.010) | (0.968–1.012) | (0.645–0.908) | (0.552–0.918) | (0.946–1.011) | |
CI, confidence interval; Ktrans, volume transfer constant from the plasma compartment to the extravascular extracellular space; Kep, rate constant for transfer between extravascular extracellular space and the blood compartment; Ve, volume of extravascular extracellular space per unit volume of tissue; iAUC, initial area under enhancement curve.