Figure 5.

Expression of P-gp, p53, Bcl-2 and Bax in the three groups, as detected by western blot assay. (A) Protein expression was examined using western blotting and recorded with a scanner system. (B) The relative expression of target proteins (compared with β-actin protein or histone H3 protein expression) in the three groups. *Compared with the control or DDP groups, the NDP group exhibited significantly lower or higher expression of the target poteins (P<0.05). DDP, cisplatin; NDP, nedaplatin; P-gp, P-glycoprotein; p53, tumor protein 53; Bcl-2, B-cell lymphoma 2; Bax, Bcl-2-associated X protein.