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. 2016 Feb 17;11(4):2371–2378. doi: 10.3892/ol.2016.4235

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Copyright: © Dong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Representative images showing ALK expression in lung cancer. Immunohistochemistry was performed using an antibody against ALK on formalin-fixed paraffin-embedded tissue sections collected from non-small cell lung cancer patients who were never-smokers. Hematoxylin and eosin staining was additionally performed on the sections. (A) ALK protein was absent in EML4-ALK-negative carcinoma. (B) ALK protein was aberrantly expressed in EML4-ALK-positive carcinoma. ALK, anaplastic lymphoma kinase; EML4, echinoderm microtubule-associated protein-like 4.