Table II.
Univariate analysis of the prognostic factors for survival rate in patients with limited-stage small-cell lung cancer.
| OS rate, % | ||||
|---|---|---|---|---|
| Characteristic | MST, months | 1-Year | 3-Year | P-value |
| Age | ||||
| <65 years | 28.1 | 88 | 44 | 0.111 |
| ≥65 years | 22.4 | 90 | 32 | |
| Gender | ||||
| Male | 26.4 | 88 | 41 | 0.087 |
| Female | 38.5 | 92 | 52 | |
| ECOG PS | ||||
| 0–1 | 28.1 | 89 | 43 | 0.427 |
| 2 | 22.4 | 80 | 33 | |
| Weight loss | ||||
| <5 | 27.4 | 89 | 43 | 0.948 |
| ≥5 | 34.4 | 73 | 44 | |
| Smoking status | ||||
| Yes | 26.1 | 87 | 40 | 0.027 |
| No | 38.5 | 92 | 51 | |
| TRT | ||||
| Yes | 30.2 | 90 | 46 | 0.001 |
| No | 19.1 | 78 | 25 | |
| CT cycles | ||||
| <4 | 25.1 | 79 | 48 | 0.601 |
| ≥4 | 27.5 | 89 | 43 | |
| PCI | ||||
| Yes | 38.8 | 96 | 53 | 0.000 |
| No | 21.5 | 82 | 35 | |
| Timing of PCI | ||||
| Early PCI | 32.6 | 92 | 50 | 0.361 |
| Late PCI | 40.9 | 99 | 55 | |
OS, overall survival; MST, median survival time; ECOG PS, Eastern Cooperative Oncology Group performance score; TRT, thoracic radiotherapy; CT, chemotherapy; PCI, prophylactic cranial irradiation.