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. 2016 Mar 30;6:23817. doi: 10.1038/srep23817

Figure 4. Western blot analysis of pramipexole-induced hypothermia on the apoptosis-related proteins and PI3K/AKT/GSK3β pathway in the brains of SAH rats.

Figure 4

(A) Western blot analysis of the protein levels of Bcl-2, Bax and active-caspase-3 in brain tissues. (B) Statistical analysis of Bcl-2, Bax and caspase-3 activation in brain tissues. Data are expressed as means ± SEM. *p < 0.05, **p < 0.01 vs. sham group; #p < 0.05, ##p < 0.01 vs. SAH group, n = 6. (C) Western blot detection of phosphorylation of PI3K, AKT and GSK3β in brain tissues. (D) Statistical analysis of phosphorylation of PI3K, AKT and GSK3β in brain tissues. Phosphorylation levels were evaluated by the ratio of phosphoprotein to total protein. Data are expressed as means ± SEM. *p < 0.05 vs. sham group; #p < 0.05 vs. SAH group, n = 6. PPX: pramipexole.