Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of prediction scores of in silico methods.
| In silico methods | Prediction |
|---|---|
| SIFT | Deleterious |
| PROVEAN | Deleterious |
| PolyPhen 2 | Probably damaging |
| SNAP | Nonneutral |
| iStable | Decrease protein stability |
| MUpro (DDG) | Decrease protein stability |
| MuStab (DDG) | Decrease protein stability |
| I-Mutant Suite (DDG) | Decrease protein stability |
