Skip to main content
. 2016 Mar 16;2016:3191638. doi: 10.1155/2016/3191638

Figure 1.

Figure 1

Antiallodynic effects of acute treatment with RSV, RSV + RO, and PGB, dosed orally, on hindpaw withdrawal threshold (g) to mechanical stimulation in the fibromyalgia model induced by reserpine in mice. Pregabalin was used as a positive control drug. Mechanical hypersensitivity was assessed before (baseline) and on the 4th day after onset of reserpine administration (0.25 mg/kg, s.c., once a day for three days). Data are presented as mean ± SEM. ∗∗ p < 0.001 compared to control (SAL-SAL), # p < 0.05 compared to RES-SAL group, ## p < 0.01 compared to RES-SAL group, and §§ p < 0.01 compared to RES-RSV-RO. Statistical analysis was performed by one-way ANOVA followed by Bonferroni's post hoc test. n = 7 to 11 mice/group.