Skip to main content
. 2016 Mar 24;12(3):861. doi: 10.15252/msb.20156520

Figure EV4. Temporal DMR stability assessment by clustering DNA methylation of CpGs in ngDMRs.

Figure EV4

  • A, B
    Hierarchical clustering (Euclidean distance) of methylation of all CpGs in ngDMRs that are not subject to SNPs in any sample. Only CpGs with a minimum coverage of 10 reads in all samples were considered. Clustering occurs by sample, not by year, suggesting high maintenance of CpG methylation levels for each sample over time. (A) Children (n = 4,682 CpGs), (B) mothers (n = 7,857 CpGs).