Table 1.
SERPINB12 Tissue Distribution Summary.
| Tissue | Scoringa | Cell Type Specificity | HPAb Detection |
|---|---|---|---|
| Adrenal gland | 2.0 | Adrenal cortical cells | High |
| Bladder | 1.0 | Detrusor muscle | Medium |
| Bone marrow | 0.5 | Hematopoietic cells | Low |
| Breast | 1.0 | Large duct epithelium; terminal duct lobular unit | Medium |
| Bronchus | 1.0 | Bronchiolar epithelium; smooth muscle | Medium |
| Cerebellum | 1.3 | Granular cells; Purkinje cells; neurons/axons | High |
| Cerebral cortex | 0.5 | Axons; neuropil | Low |
| Esophagus | 1.7 | Squamous epithelium; smooth muscle | Medium |
| Fallopian tube | 1.5 | Epithelium; vascular tissue; smooth muscle | Medium |
| Heart | 2.0 | Myocytes | Medium |
| Intestine, colon | 1.1 | Epithelium | Medium |
| Intestine, rectum | 1.0 | Epithelium | Medium |
| Intestine, small intestine | 2.0 | Epithelium | Medium |
| Kidney | 2.5 | Tubular epithelium | Medium |
| Liver | 2.0 | Hepatocytes | Medium |
| Lung | 1.0 | Epithelium; alveolar macrophages | Low |
| Muscle, skeletal | 2.0 | Myocytes | Low |
| Ovary | 1.0 | Fibrovascular tissue | ND |
| Pancreas | 2.0 | Acinar cells; duct cells | Medium |
| Pituitary gland | 1.3 | Pituicytes | NA |
| Placenta | 1.0 | Cytotrophoblasts | Medium |
| Prostate | 1.0 | Fibromuscular stroma | Low |
| Skin | 1.0 | Squamous epithelium; eccrine duct | Medium |
| Spleen | 0.0 | ND | |
| Stomach | 1.5 | Superficial foveolar epithelium | High |
| Testis | 1.0 | Sertoli cells | Low |
| Thymus | 1.7 | Macrophages; epithelium | NA |
| Thyroid | 1.0 | Follicular epithelium | Medium |
| Tonsil | 1.2 | Squamous epithelium; macrophages | Low |
| Trachea | 1.0 | Epithelium | NA |
| Uterus | 1.2 | Endometrium; smooth muscle | Medium |
NA, not available; ND, not detected.
a
Tissue arrays scored as no staining (0), mild (1), moderate (2), or strong (3). Scores given are average of multiple sections and tissue arrays (n≥2).
b
From the Human Protein Atlas (HPA; www.proteinatlas.org).