. 2014 Jul 18;22(4):452–461. doi: 10.1177/1933719114542009

Table 1.

Immunization With SPRASA Leads to a Reduction in Fertility in Female Mice.^a,b

Immunization	Number of Mice Pregnant After Each Mating
Immunization	First	Second	Third	Forth	Fifth	Summary
SPRASA	2/10	1/8	0/8	0/8	0/5	3/10 (30%)	P = .001
KLH	4/8	4/4	–	–	–	8/8 (100%)	P = .001

Abbreviations: KLH, keyhole limpet hemocyanin; SPRASA, sperm protein reactive with antisperm antibody.

^aAnimals were euthanized to confirm pregnancy. Pregnancy is defined as confirmed fetuses at day 12 postcoitus.

^bThe P value refers to a chi-square test comparing the total number of pregnant mice over all matings in the SPRASA-immunized and control KLH-immunized groups.