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. 2016 Mar 4;113(12):3185–3190. doi: 10.1073/pnas.1521255113

Fig. S8.

Fig. S8.

Isogenic NPCs-derived neurons mimic the neurite outgrowth and synapse formation defects of RTT neurons in 3D. (A) Representative images of isogenic cell-derived neurons after neuronal differentiation in 3D. (Scale bar, 50 μm.) (B) Representative images of isogenic cell-derived neurons showing Syn1 puncta on Map2-positive neurites. (Scale bar, 20 μm.) (C) Quantification of neurite length after neuronal differentiation in 3D. Bars represent means; **P < 0.01; n = 3. (D) Quantification of Syn1 puncta on Map2 neurites. Bars represent means of 50 neurons per condition; **P < 0.01; n = 3.