Fig. S8.

Young’s modulus of the engineered construct after 7 d of static stretching and preimplantation. Engineered constructs seeded with endothelial cells and fibroblasts and cultured under static stretching conditions were mounted within the Biodynamic test instrument. Scaffolds were stretched along the static stretching direction (vertical, in the direction of the vessel-like structures) and orthogonal to the static stretching direction (horizontal, orthogonal to the vessel-like structures orientation direction). No significant change in Young’s modulus was observed between the vertically and horizontally stretched samples or with the unstretched controls. This suggests that the implanted structures featured similar initial mechanical properties preimplantation and strengthens the hypothesis that mechanical properties improve with better integration with the host tissue.