Table S1.
Quantification (pg/mol) of secreted angiogenic factors by cells embedded within Gelfoam scaffolds and fibrin gels as estimated with the Q-Plex array chemiluminescent assay
| Examined sample | Ang2 | FGF | HGF | IL8 | PDGF-ββ | TIMP1 | TIMP2 | TNF | VEGF |
| Control Gelfoam | 880.582 | −15.353 | 531.994 | 864.563 | 2.262 | 5,084.963 | 398.651 | 20.485 | −336.008 |
| Cyclic stretching | 1,041.364 | −26.367 | 330.228 | 922.486 | 6.186 | 6,068.235 | 274.112 | 16.809 | −118.243 |
| Static stretching | 1,182.525 | −16.788 | 311.275 | 1,010.105 | 5.818 | 5,345.602 | 499.167 | 21.853 | −324.327 |
| Free-floating fibrin-day 2 | 2,234.360 | 532.745 | 1,102.695 | 1,172.465 | 30.418 | 4,381.490 | 2,257.460 | 36.497 | −122.829 |
| Attached fibrin-day 2 | 2,891.382 | 410.413 | 822.812 | 1,540.140 | 52.958 | 5,057.260 | 7,483.195 | 64.958 | −137.513 |
| Fixated fibrin-day 2 | 2,558.009 | 483.981 | 1,002.798 | 1,760.108 | 38.426 | 5,676.098 | 10,568.202 | 61.013 | −139.572 |
| Free-floating fibrin-day 7 | 1,654.757 | 324.372 | 2,530.675 | 1,454.145 | 34.388 | 4,969.953 | 7,994.456 | 65.847 | −133.553 |
| Attached fibrin-day 7 | 4,485.380 | 203.003 | 7,897.495 | 1,571.455 | 75.672 | 4,583.800 | 12,755.795 | 100.317 | −105.214 |
| Fixated fibrin-day 7 | 2,153.042 | 379.705 | 6,602.625 | 1,760.895 | 37.920 | 5,414.038 | 13,596.653 | 64.772 | −132.187 |
We demonstrate here the quantitative results of cytokine secretions under the different mechanical manipulations. For the fibrin gel, we compared fibrin attached to the plate vs. fixated fibrin in the PDMS µposts vs. free-floating fibrin. The presented results are after subtracting the initial level of the cytokine in the medium.