Fig. (1).

NGF target cells (NTC). Cell types belonging to nervous and immune system as well as some structural cells, all previously reported to be receptive (NGFR-bearing cells) and producers of NGF, are drawn in panel A. Crosstalk occurs via interplays with the other soluble factors, comprising cytokines, neuropeptides, growth as well as angiogenic/angiostatic factors, and other cell mediators, including soluble receptors. The main recognized functional activities are summarized in B. Abbreviations: RGCs, retinal ganglion cells; BPCs, bipolar cells; FBs/myoFBs, Fibroblast/myofibroblast.