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NGF tissue protection in animal models and humans.
A. NGF Therapeutic Potential Based on Animal Studies
| Type of Disorder | Species | Treatment | Outcome | Refs. |
|---|---|---|---|---|
| Postischemic Coronary Innervation | Dogs | 10ng | Protection | [93] |
| Wound healing | Mice | 1ug | Healing | [21] |
| Hypoxic-Ischemic | Young rats | 15ug | Protection | [94] |
| Encephalomyelitis | Marmosets | 100ug | Protection | [95] |
| Heart Failure | Rats | 9.15nmole | Protection | [96] |
| Nasal delivery | Rats | 10ng | Protection | [48] |
| Glaucoma | Rats | 10ug | Protection | [15] |
