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. 2015 Apr;75(4):342–354. doi: 10.1055/s-0035-1545741

Table 4 Antimycotic agents against vulvovaginal candidosis.

Polyenes (since ca. 1960):
  • Nystatin: vaginal tablets or vaginal suppositories 100 000 IE, 200 000 IE for 6-day treatment, nystatin cream, nystatin ointment

  • Amphotericin B (no longer available in Germany for vaginal treatment)

Imidazoles (since ca. 1970):
  • Clotrimazole, miconazole nitrate, econazole nitrate, fenticonazole nitrate and others in the form of vaginal tablets, vaginal suppositories, vaginal creams, skin creams (for the vulva and perineal areas). For example, 500 mg clotrimazole vaginal tablets for 1-day treatment or 600 mg fenticonazole nitrate in the form of a vaginal suppository; for 3-day treatment clotrimazole 200 mg vaginal tablets or 2 % vaginal cream; for 6-day treatment 100 mg clotrimazole vaginal tablets or 1 % vaginal cream, etc.

Oral imidazoles (since ca. 1980):
  • Ketoconazole (no longer available in Germany)

Triazoles (since ca. 1990):
  • Fluconazole 150 mg hard capsules for 1-day treatment, fluconazole 50 mg, 100 mg, 200 mg capsules

  • Itraconazole hard capsules 100 mg, 2 × 200 mg for 1-day treatment

Ciclopirox olamine (for gynacological treatment since ca. 1995):
  • Vaginal cream 10 mg/g: 50 mg daily for 6 days