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Telmisartan could inhibit angiotensin II-induced NLRP3 inflammasome activation. The inflammasome markers (NLRP3 and ASC) were detected by indirect immunostaining in HK-2 cells. HK-2 cells were treated without or with 100 nmol/L angiotensin II or with 100 nmol/L angiotensin II and 1 μmol/L telmisartan (ARB) for 12 h in serum-free medium.
