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Exciting mPFC PN does not alter behavior in the open field. CNO, whether administered at 0.5 mg/kg (striped bars) or 2.5 mg/kg (black bars) had no effect on time spent in the center or time spent in the border of an open field arena, relative to saline (white bars). CNO also had no effect on total distance moved (CNO Panel A,C, N = 7; Saline Panel A,C, N = 7; CNO Panel B,D N = 12, Saline Panel B,D N = 12). Error bars are ± SEM. Unpaired t-test.
