Table 1.
Patients’ characteristics.
| Healthy (n = 10) | Surgery (n = 9) | Sepsis (n = 20) | p-Value | |
|---|---|---|---|---|
| Age (years) (IQR) | 55 (49–74) | 70 (55–75) | 64 (55–75) | 0.63 |
| Male sex (%) | 7 (70.0) | 4 (44.4) | 12 (60.0) | 0.52 |
| BMI (kg/m2) (IQR) | - | 24.3 (22.1–35.1) | 27.3 (30.9–22.6) | 0.72 |
| Diabetes mellitus (%) | - | 3 (33.3) | 4 (20.0) | 0.5 |
| Creatinine (mg/dL) (IQR) | - | 0.9 (0.6–1.0) | 0.8 (0.7–1.3) | 0.71 |
| Hemoglobin (g/dL) (IQR) | - | 11.3 (10.1–12.0) | 9.3 (8.4–9.6) | <0.0001 |
| Platelets (109 cells/nL) (IQR) | - | 255.0 (168.0–296.0) | 193.5 (173.0–257.8) | 0.32 |
| White cells (109 cells/nL) (IQR) | - | 10.5 (8.8–12.5) | 17.5 (14.3–21.1) | 0.02 |
| Neutrophil (109 cells/nL) (IQR) | - | 85.5 (84.9–87.9) | 86.0 (76.5–93.0) | 0.89 |
| Eosinophil (109 cells/nL) (IQR) | - | 0.2 (0.1–0.2) | 0.0 (0.0–1.5) | 0.69 |
| Monocyte (109 cells/nL) (IQR) | - | 4.9 (2.5–6.4) | 4.3 (3.5–6.0) | 0.91 |
| Lymphocyte (109 cells/nL) (IQR) | - | 9.3 (4.1–11.7) | 5.0 (2.9–10.5) | 0.26 |
| Albumin (g/L) (IQR) | - | 31.0 (26.5–38.5) | 22.0 (19.0–26.0) | <0.0001 |
| PCT (ng/mL) (IQR) | - | 0.1 (0.0– 0.2) | 3.1 (0.6–21.8) | <0.0001 |
| CRP (mg/dL) (IQR) | - | 6.6 (2.8– 25.0) | 170.5 (113.0–230.0) | <0.0001 |
| Lactate (mmol/L) (IQR) | - | 0.9 (0.8–1.7) | 1.5 (1.2–2.5) | 0.05 |
| Fluid administration within first 24 h (L) (IQR) | - | 4.9 (3.0–5.0) | 5.2 (3.5–7.0) | 0.13 |
| Urine output within first 24 h (L) (IQR) | - | 1.9 (1.3–2.3) | 3.4 (2.6–4.3) | <0.0001 |
| SOFA (points) (IQR) | - | 5.0 (0.5–6.0) | 6.0 (3.3–8.0) | 0.06 |
| APACHE II (points) (IQR) | - | 9.0 (4.0–10.5) | 11.5 (8.5–16.8) | 0.03 |
| Vasopressors (h) (IQR) | - | 2.5 (0.0–31.0) | 30.0 (2.0–68.8) | 0.11 |
| MV (h) (IQR) | - | 3.0 (0.3–7.0) | 3.0 (0.0–45.5) | 0.55 |
| LOS ICU (days) (IQR) | - | 1.0 (1.0–3.0) | 7.0 (5.0–12.0) | <0.0001 |
| 28-day mortality (%) | - | 0 (0.0) | 0 (0.0) | - |
Categorical and continuous variables are presented as n (%) and median (interquartile ranges, IQR), respectively. Kruskal-Wallis test was used to compare categorical and continuous variables, respectively. BMI, body-mass-index; PCT, Procalcitonin; CRP, C-reactive protein, SOFA, Sequential Organ Failure Assessment score; APACHE II, Acute Physiology and Chronic Health Evaluation II score; MV, mechanical ventilation; LOS, length of stay.