Figure 1.

Overexpression of miR-29a in the murine model caused the downregulation of fibrosis in the mice livers following bile duct ligation. Sirius Red staining showed faint fibrosis in both sham operation of wide type (a) and miR-29a Tg mice (b) as well as moderate fibrosis in the –wild type mice (c) and mild fibrosis in the miR-29aTg mice (d), which was limited to the immediate vicinity of the portal area. (e) Data from the three samples per group are expressed as the mean ± SE. * indicates a p < 0.05 between the groups.