Table 2.
Results of pathway enrichment analysis on the 452 genes differentially expressed in the miR-29a-BDL vs. miR-29a-Sham comparison alone.
| Pathway Name | p Value | # of Genes in the Pathway | Pathway ID |
|---|---|---|---|
| Steroid hormone biosynthesis | 0.000021 | 8 | kegg_pathway_294 |
| Leukocyte transendothelial migration | 0.000029 | 11 | kegg_pathway_276 |
| Natural killer cell mediated cytotoxicity | 0.000347 | 10 | kegg_pathway_253 |
| Chemical carcinogenesis | 0.000356 | 7 | kegg_pathway_229 |
| Fc epsilon RI signaling pathway | 0.000914 | 7 | kegg_pathway_100 |
| Platelet activation | 0.001147 | 9 | kegg_pathway_23 |
| B cell receptor signaling pathway | 0.001389 | 7 | kegg_pathway_65 |
| Osteoclast differentiation | 0.002132 | 9 | kegg_pathway_135 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 0.002642 | 6 | kegg_pathway_1 |
| Retinol metabolism | 0.002727 | 6 | kegg_pathway_57 |
| Bile secretion | 0.002771 | 6 | kegg_pathway_291 |
| Phagosome | 0.003856 | 10 | kegg_pathway_194 |
| Hypertrophic cardiomyopathy (HCM) | 0.005919 | 6 | kegg_pathway_279 |
| Energy metabolism | 0.011458 | 8 | kegg_pathway_16 |
| Pentose and glucuronate interconversions | 0.021195 | 3 | kegg_pathway_285 |
| Metabolic pathways | 0.021733 | 31 | kegg_pathway_235 |
| Focal adhesion | 0.022124 | 9 | kegg_pathway_187 |
| Inositol phosphate metabolism | 0.022784 | 4 | kegg_pathway_49 |
| Viral carcinogenesis | 0.024087 | 9 | kegg_pathway_216 |
| Axon guidance | 0.025580 | 7 | kegg_pathway_264 |
| Antigen processing and presentation | 0.025778 | 5 | kegg_pathway_269 |
| Viral myocarditis | 0.026037 | 5 | kegg_pathway_47 |
| Linoleic acid metabolism | 0.027978 | 3 | kegg_pathway_263 |
| Dilated cardiomyopathy | 0.029280 | 5 | kegg_pathway_277 |
| Autoimmune thyroid disease | 0.039891 | 4 | kegg_pathway_64 |
| Biosynthesis of antibiotics | 0.040668 | 8 | kegg_pathway_274 |
| Fc gamma R-mediated phagocytosis | 0.041882 | 5 | kegg_pathway_120 |
| 2-Oxocarboxylic acid metabolism | 0.046164 | 2 | kegg_pathway_35 |
| HTLV-I infection | 0.047823 | 10 | kegg_pathway_189 |