Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Mar 2;17(3):327. doi: 10.3390/ijms17030327

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Depiction of endoplasmic reticulum (ER) redox communication by mediators. During the protein folding process, production of reactive oxygen species (ROS) by possible surrounding sources, such as NADPH oxidase 4 (Nox4), NADPH-P450 reductase (NPR), and GSH topologies, along with their functions in the outer ER environment. NADPH, Nicotinamide adenine dinucleotide phosphate; G6P, glucose-6-phosphate; 6PG, 6-phospho gluconate; Nox4, NADPH oxidase 4; GSH, glutathione; GSSG, glutathione disulphide; ERO1, ER oxidoreductin 1; PDI, protein disulfide isomerase. CYP/p450; Cytochrome p450.