Table 6.
Pi-Pi interaction parameters for each compound and PDK residues.
| Receptor | Compound | End 1 | End 2 | Distances (Å) |
|---|---|---|---|---|
| PDK1 | ZINC12296427 | PHE65 | ZINC12296427 | 4.08 |
| ZINC12389251 | PHE65 | ZINC12389251 | 4.25 | |
| AZD7545 | PHE65 | AZD7545 | 4.64 | |
| PDK2 | ZINC12296427 | PHE31 | ZINC12296427 | 3.99 |
| PHE31 | ZINC12296427 | 4.09 | ||
| PHE44 | ZINC12296427 | 5.79 | ||
| ZINC12389251 | PHE31 | ZINC12389251 | 4.01 | |
| PHE31 | ZINC12389251 | 3.99 | ||
| AZD7545 | PHE31 | AZD7545 | 4.83 | |
| PDK3 | ZINC12296427 | PHE35 | ZINC12296427 | 4.27 |
| PHE35 | ZINC12296427 | 4.36 | ||
| AZD7545 | PHE35 | AZD7545 | 4.36 | |
| PHE48 | AZD7545 | 4.96 |