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. 2016 Mar 18;17(3):404. doi: 10.3390/ijms17030404

Figure 3.

Figure 3

Haloperidol decreases the activity of lysosomal proteases. THP-1 macrophages cells incubated in lipoprotein-deficient serum (LPDS) medium with LDL were kept untreated (control) or treated with haloperidol (10 and 25 µM) for 30 min, then DQ-BSA was added for 30 min and analyzed by flow cytometry. Results are mean ± SEM of three independent experiments. MFI, median fluorescence intensity. Statistical comparisons shown are haloperidol versus control (*** p < 0.001 and **** p < 0.0001).