Table 2.
Amino acid sequence identity of STAT between different species (%) (Sh, Dr, Ga, Tr and Hs mean S. hasta, Danio rerio, Gasterosteus aculeatus, Takifugu rubripes and Homo sapiens, respectively). Amino acid sequence identity of the same STAT isoform between species is shaded. Values in the bottom line represent the means ± SEM from identity of the same STAT isoform.
| Species | STAT1 | STAT2 | STAT3 | STAT4 | STAT5.1 | STAT5.2 | STAT6 | |||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sh | Dr | Ga | Tr | Hs | Sh | Dr | Ga | Tr | Hs | Sh | Dr | Ga | Tr | Hs | Sh | Dr | Ga | Tr | Hs | Sh | Dr | Ga | Tr | Hs | Sh | Dr | Ga | Hs | Sh | Dr | Ga | Tr | Hs | |
| Sh S1 | *** | 61.5 | 80.4 | 80.7 | 67.7 | 42.2 | 43.3 | 44.1 | 44.7 | 39.4 | 50.4 | 49.4 | 50.3 | 51.0 | 50.5 | 48.3 | 51.3 | 49.7 | 48.9 | 49.2 | 27.4 | 27.3 | 27.8 | 27.7 | 27.1 | 26.7 | 27.3 | 26.4 | 27.0 | 24.2 | 25.1 | 24.5 | 23.7 | 23.0 |
| Dr S1 | – | *** | 63.3 | 62.5 | 61.9 | 42.7 | 42.5 | 42.4 | 42.7 | 37.6 | 47.3 | 47.4 | 47.8 | 47.7 | 47.9 | 46.7 | 49.8 | 48.7 | 47.7 | 48.7 | 28.0 | 28.2 | 27.9 | 27.7 | 27.6 | 27.4 | 27.0 | 26.7 | 26.7 | 26.0 | 27.0 | 25.2 | 25.0 | 25.2 |
| Ga S1 | *** | 83.8 | 67.6 | 41.3 | 42.5 | 42.9 | 44.4 | 39.7 | 50.3 | 50.0 | 50.5 | 50.9 | 51.1 | 47.4 | 50.1 | 48.6 | 48.8 | 48.7 | 26.7 | 26.6 | 26.9 | 26.8 | 26.7 | 26.1 | 26.2 | 25.8 | 26.4 | 24.0 | 25.4 | 24.4 | 23.9 | 23.1 | ||
| Tr S1 | *** | 67.7 | 40.9 | 41.5 | 42.4 | 43.6 | 39.3 | 49.7 | 48.8 | 49.3 | 49.9 | 50.0 | 47.9 | 51.2 | 49.0 | 48.8 | 49.5 | 26.3 | 26.5 | 26.7 | 26.7 | 26.6 | 25.5 | 26.2 | 25.6 | 26.0 | 24.8 | 25.2 | 24.0 | 23.3 | 22.0 | |||
| Hs S1 | *** | 44.2 | 46.4 | 45.3 | 46.1 | 42.3 | 51.4 | 51.2 | 51.6 | 52.2 | 51.8 | 53.1 | 53.6 | 53.3 | 52.3 | 53.3 | 28.0 | 28.0 | 27.9 | 27.8 | 28.6 | 27.4 | 28.3 | 27.0 | 28.4 | 26.8 | 26.7 | 26.2 | 25.3 | 23.7 | ||||
| Sh S2 | *** | 53.6 | 69.7 | 69.6 | 38.3 | 41.7 | 41.4 | 41.3 | 41.9 | 41.4 | 39.0 | 40.9 | 39.9 | 38.9 | 40.4 | 24.3 | 24.2 | 23.9 | 24.1 | 24.1 | 23.1 | 23.5 | 23.1 | 24.3 | 24.2 | 24.4 | 25.0 | 24.2 | 22.3 | |||||
| Dr S2 | *** | 56.9 | 58.5 | 36.3 | 42.7 | 41.7 | 42.1 | 43.0 | 42.9 | 39.8 | 40.9 | 39.7 | 39.2 | 41.5 | 27.1 | 27.0 | 27.3 | 27.4 | 26.2 | 27.2 | 26.7 | 27.2 | 26.4 | 25.0 | 25.3 | 26.1 | 24.3 | 22.6 | ||||||
| Ga S2 | *** | 74.5 | 43.1 | 43.2 | 43.0 | 43.2 | 43.5 | 43.2 | 39.5 | 41.1 | 40.1 | 39.1 | 41.1 | 25.3 | 25.4 | 26.0 | 25.9 | 26.5 | 24.6 | 25.4 | 24.9 | 26.3 | 24.9 | 25.4 | 25.8 | 24.6 | 23.2 | |||||||
| Tr S2 | *** | 41.9 | 44.3 | 44.6 | 44.3 | 44.6 | 44.1 | 40.9 | 41.7 | 40.7 | 40.9 | 41.8 | 26.8 | 26.6 | 26.8 | 26.5 | 27.0 | 26.4 | 27.0 | 26.6 | 27.0 | 25.7 | 26.2 | 26.4 | 26.3 | 24.8 | ||||||||
| Hs S2 | *** | 36.9 | 36.2 | 35.8 | 36.8 | 37.5 | 38.5 | 41.0 | 40.3 | 40.0 | 40.3 | 23.8 | 24.4 | 23.3 | 23.3 | 23.9 | 23.9 | 24.0 | 24.8 | 23.2 | 20.7 | 23.5 | 22.5 | 21.6 | 20.6 | |||||||||
| Sh S3 | *** | 95.7 | 97.1 | 96.3 | 88.7 | 47.5 | 48.6 | 47.9 | 47.1 | 48.5 | 29.1 | 29.5 | 29.5 | 29.3 | 29.7 | 29.3 | 29.2 | 29.5 | 30.0 | 22.7 | 25.9 | 24.9 | 23.8 | 22.0 | ||||||||||
| Dr S3 | *** | 92.3 | 94.5 | 88.5 | 47.4 | 48.9 | 48.1 | 47.5 | 48.7 | 28.5 | 29.2 | 29.1 | 28.8 | 28.8 | 28.9 | 28.7 | 29.1 | 28.9 | 22.5 | 25.0 | 24.9 | 23.5 | 21.2 | |||||||||||
| Ga S3 | *** | 95.3 | 87.9 | 47.9 | 49.0 | 48.0 | 47.3 | 49.2 | 28.4 | 29.1 | 29.0 | 28.7 | 29.2 | 28.5 | 28.4 | 28.9 | 29.3 | 22.7 | 25.2 | 25.1 | 23.2 | 21.6 | ||||||||||||
| Tr S3 | *** | 88.0 | 47.8 | 49.1 | 48.2 | 47.4 | 48.6 | 28.8 | 29.3 | 29.3 | 29.1 | 29.8 | 28.8 | 29.2 | 29.3 | 30.1 | 22.6 | 25.4 | 25.1 | 23.6 | 22.3 | |||||||||||||
| Hs S3 | *** | 47.0 | 48.8 | 47.9 | 46.8 | 48.2 | 28.2 | 28.6 | 28.7 | 28.6 | 28.6 | 28.3 | 28.9 | 28.7 | 28.8 | 22.4 | 25.2 | 25.0 | 24.0 | 22.6 | ||||||||||||||
| Sh S4 | *** | 73.2 | 86.0 | 81.7 | 59.1 | 27.0 | 28.0 | 27.7 | 27.5 | 28.4 | 27.7 | 27.9 | 27.9 | 28.5 | 25.8 | 25.7 | 25.4 | 25.9 | 25.8 | |||||||||||||||
| Dr S4 | *** | 74.8 | 72.4 | 61.0 | 28.6 | 28.9 | 28.8 | 28.6 | 28.9 | 27.8 | 27.9 | 27.9 | 28.6 | 25.1 | 26.6 | 25.4 | 26.4 | 26.4 | ||||||||||||||||
| Ga S4 | *** | 86.1 | 59.3 | 28.4 | 29.6 | 29.2 | 29.0 | 29.3 | 28.7 | 28.0 | 28.5 | 29.0 | 24.9 | 26.5 | 25.3 | 25.3 | 25.2 | |||||||||||||||||
| Tr S4 | *** | 58.3 | 27.7 | 28.3 | 28.2 | 27.9 | 28.4 | 28.3 | 27.9 | 28.0 | 28.3 | 25.0 | 26.4 | 25.4 | 25.5 | 25.3 | ||||||||||||||||||
| Hs S4 | *** | 29.4 | 29.8 | 29.5 | 29.2 | 29.8 | 28.8 | 28.9 | 28.7 | 29.5 | 24.8 | 25.6 | 25.3 | 25.9 | 24.1 | |||||||||||||||||||
| Sh S5.1 | *** | 92.6 | 94.3 | 94.9 | 79.1 | 81.0 | 82.7 | 81.5 | 78.0 | 34.9 | 34.6 | 39.0 | 34.9 | 36.7 | ||||||||||||||||||||
| Dr S5.1 | *** | 94.1 | 93.6 | 80.1 | 82.2 | 83.9 | 82.2 | 79.1 | 35.9 | 35.0 | 39.1 | 35.5 | 37.9 | |||||||||||||||||||||
| Ga S5.1 | *** | 96.3 | 79.6 | 82.3 | 82.8 | 82.0 | 78.2 | 35.3 | 34.4 | 39.4 | 35.2 | 36.9 | ||||||||||||||||||||||
| Tr S5.1 | *** | 79.9 | 82.7 | 83.2 | 82.5 | 78.7 | 35.5 | 34.8 | 39.5 | 35.5 | 37.7 | |||||||||||||||||||||||
| Hs S5B | *** | 74.2 | 74.2 | 74.8 | 93.7 | 34.6 | 33.9 | 37.9 | 35.4 | 37.8 | ||||||||||||||||||||||||
| Sh S5.2 | *** | 79.5 | 89.6 | 73.6 | 35.6 | 35.5 | 39.0 | 35.2 | 37.2 | |||||||||||||||||||||||||
| Dr S5.2 | *** | 78.6 | 74.5 | 35.5 | 35.6 | 38.6 | 35.1 | 37.0 | ||||||||||||||||||||||||||
| Ga S5.2 | *** | 74.0 | 34.2 | 34.0 | 38.0 | 35.5 | 37.0 | |||||||||||||||||||||||||||
| Hs S5A | *** | 34.6 | 34.1 | 38.2 | 35.2 | 37.7 | ||||||||||||||||||||||||||||
| Sh S6 | *** | 50.9 | 58.3 | 57.6 | 38.3 | |||||||||||||||||||||||||||||
| Dr S6 | *** | 58.7 | 53.7 | 37.3 | ||||||||||||||||||||||||||||||
| Ga S6 | *** | 74.4 | 41.4 | |||||||||||||||||||||||||||||||
| Tr S6 | *** | 37.4 | ||||||||||||||||||||||||||||||||
| Hs S6 | *** | |||||||||||||||||||||||||||||||||
| Values | 69.71 ± 2.72 | 54.24 ± 4.43 | 92.43 ± 1.20 | 71.19 ± 3.54 | 88.45 ± 2.41 | 78.30 ± 2.48 | 50.80 ± 3.85 | |||||||||||||||||||||||||||
“***” represents the amino acid sequence identity of the same STAT.