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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 Feb 4;55(10):3455–3458. doi: 10.1002/anie.201600309

Scheme 1.

Scheme 1

Problems associated with an application of catalytic enantioselective allylic substitution (EAS) to synthesis of rhopaloic acid B and a possible solution. Abbreviations: P, protecting group; LG, leaving group; pin, pinacolato.