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. Author manuscript; available in PMC: 2016 Mar 30.
Published in final edited form as: Pediatr Res. 2012 Feb 15;71(4 Pt 1):338–344. doi: 10.1038/pr.2011.74

Figure 2.

Figure 2

Tricarboxylic acid (TCA)-cycle intermediates and the change in their normalized m/z signal intensity over the first 72 h of age. (a) α-Ketoglutaric acid, (b) fumaric acid, (c) malic acid, and (d) succinyl-CoA. Each individual line represents the change in the specified metabolite over time for each primate (P1–6) plotted independently. Each metabolite slowly increases over the time course demonstrated on the x-axis. After mixed-model ANOVA, post hoc Dunnett’s tests comparing individual time points to time point zero are demonstrated: *P < 0.05; †P < 0.01; ‡P < 0.001.