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. 2016 Jan 27;291(12):6433–6446. doi: 10.1074/jbc.M115.693671

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© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — Time kinetic changes in the expression of CTGF, AR, and fibrosis-related genes and collagen deposition in bleomycin-challenged lungs. A–E, time kinetics in the expression of CTGF, AR, collagen 3A1, fibronectin, and elastin in the lungs of mice exposed to intratracheal bleomycin (BLM). F, kinetic changes of soluble collagen protein deposition in lungs as measured by Sircol assay. Data represent mean ± S.E. of a minimum of four mice treated with bleomycin. *, p < 0.05; **, p < 0.01; ***, p < 0.001.