FIGURE 1.

Alignment of amino sequences of P. pastoris Mit1 (GenBank^TM accession number CAY70887) and H. polymorpha Mpp1 (GenBank^TM accession number AAO72735) by the ClustalX program. The amino acids are shown by one-letter codes. Gaps were introduced to maximize the similarity. The zinc finger domain between aa 29 and 73 in Mpp1 is underlined. The solid black circles represent cysteine residues of Zn(II)₂Cys₆ domain. A line below the alignment was used to mark highly conserved positions. Three characters (asterisk, colon, and period) were used: asterisk, indicates positions that have a single, fully conserved residue; colon, indicates positions that are fully conserved in the “strong” groups; period, indicates positions that are fully conserved in the “weak” groups. The strong and weak groups were determined by ClustalX.