Fig. 1.
The discovery and verification of biomarker candidates for the differential diagnosis of CCC and PDAC. The experimental workflow used for this study can be divided into two phases (A). During the discovery phase, the protein list resulting from the LC-MS experiment was filtered in several steps (B). This led to the selection of proteins for the verification by immunohistochemistry (IHC). Abbreviations: m/z, mass to charge ratio; RT, retention time; ROC, receiver operating characteristic; pFDR, t test p value after adjustment (Benjamini, Hochberg); FC, fold change.