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. 2016 Jan 10;15(3):892–905. doi: 10.1074/mcp.M115.053280

Fig. 4.

Fig. 4.

Enrichment of known and novel specificity sequence motifs in SMYD2-targeted Kme1 sites. A, Sequence motifs enriched in the Kme1 sites identified in parental KYSE-150 cells or in SMYD2-overexpressing cells. B, Fold-increase in the occurrence of each enriched sequence motif compared with the background proteome based on motif-X analysis. See Supplemental Table S4 for complete motif-X results. C, Normalized peptide ratios for Kme1 sites that contained an enriched sequence motif (black) and Kme1 sites that did not (blue). p value calculation is based on the normalized peptide ratios of Kme1 sites in each group using Student's t test. D, Normalized peptide ratios for Kme1 sites containing the indicated enriched sequence motif. p value calculations are based on comparison of the normalized peptide ratios of Kme1 sites in “No motif” using Student's t test. n.s., not significant; *p value ≤ 0.0005; **p value ≤ 0.00005, ***p value ≤ 0.000005. 1, Lanouette et al., 2015; 2, Rathert et al., 2008; 3, Dhayalan et al., 2011.