Table 1.

Patients’ clinical details

N	Target	Diagnosis	Center	Age	Sex	Disease duration	BDI a	HAM-D b	YBOCSb/comorbid depression	Medication
1	CG25	MDD	Berlin	49	F	33	35	22	NA	Loracepam, amitriptyline, quetiapine, topiramate
2	CG25	MDD	Berlin	61	F	23	22	23	NA	Loracepam, clomipramine, fluvoxamine, lithium, gabapentine, mirtazapine
3	CG25	MDD	Berlin	48	F	16	46	30	NA	Lithium, quetiapine, duloxetine
4	CG25	MDD	Berlin	60	F	20	36	34	NA	Lithium, tranylcypromine, pregabaline, quetiapine
5	CG25	MDD	Berlin	36	M	16	57	24	NA	No medication
6	CG25	MDD	Berlin	50	M	34	41	32	NA	Zopiclone, quetiapine, trimipramine
7	CG25	MDD	Berlin	55	M	20	37	21	NA	Pregabalin, agomelatine, quetiapine, levothyroxine
8	BNST	MDD	Leuven	58	M	34	10	21	NA	Reboxetine, zoplicone, clorazepat, allopurinol, trazodone
9	BNST	MDD	Leuven	42	F	25	32	27	NA	Lormetazepam, venlafaxine, lorazepam, promethiazine, trazodone, elthyrone
10	BNST	MDD	Leuven	51	F	5	17	27	NA	No medication
11	BNST	MDD	Leuven	55	M	11	14	21	NA	Venlafaxine RT, lithiumcarbonate
12	BNST	MDD	Leuven	45	M	9	44	23	NA	Clomipramine, trazodone, lithiumcarbonate
13	BNST	MDD	Leuven	46	M	9	6	26	NA	Duloxetine
14	BNST	MDD	Leuven	50	F	14	5	25	NA	Aripiprazole, clomipramine, lithiumcarbonate, trazodone, lormetazepam, simvastatine
15	BNST	OCD	Leuven	32	M	17	20	21	32/No	Clomipramine, quetiapine, fluvoxamine, clonazepam
16	BNST	OCD	Leuven	52	M	34	10	27	35/Yes	Prazepam
17	BNST	OCD	Leuven	60	M	52	NA	29	36/Yes	Buspirone, fluvoxamine, clonazepam
18	BNST	OCD	Leuven	51	F	33	35	14	37/Yes	Alprazolam
19	BNST	OCD	Leuven	34	M	22	10	20	37/No	Bisoprolol, melatonine, alprazolam

Abbreviations: BDI, Beck depression inventory; BNST, bed nucleus of stria terminali; F, female ; HAM-D, Hamilton depression inventory; M, male; MDD, major depressive disorder; NA, not available; OCD, obsessive compulsive disorder; YBOCS, Yale-Brown Obsessive Compulsive Scale.

^aAs assessed at the time of recording.

^bAs assessed at the preoperative baseline of the clinical study.