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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: Biochem Pharmacol. 2016 Mar 2;106:94–103. doi: 10.1016/j.bcp.2016.02.020

Fig. 2. AHR mediates TCDD-stimulated increases in LAT1 mRNA.

Fig. 2

A & B, MCF-7 cells were transfected with siRNAs that were either non-targeting (cRNAi) or AHR targeting (AHRi) and then treated with DMSO vehicle (Veh) or TCDD (10 nM) for 6 hrs. C & D, MCF-7 cells were treated vehicle or TCDD (10 nM) in the absence (controls) or presence of CH-223191 (10 μM) for 6 hrs. A-D, AHR, LAT1, CYP1A1 or GAPDH mRNA were quantified by qRT-PCR from total RNA. GAPDH mRNA levels were used to normalize samples. *, P < 0.05; **, P > 0.01. Data shown are the means ± S.E. of three independent experiments.