Table 1.

Modes and dosage regimes of administration

Preparation	Methods of administration (dosing regime)
	Repeated low dose and bolus administration	Intravenous drip	Intravenous drip
		Moderate dose infusion	Total dose infusions
	(100–510 mg)	(200–1000 mg)	> 1000 mg
Low-molecular-weight iron dextran (Cosmofer)	≤ 200 mg	≤ 1000 mg	1500 mg ~ 4–6 h (3 ha), Up to 20 mg iron/kg ~ 4–6 h + test dose
Iron sucrose (Venofer)	≤ 200 mg	≤ 200 mg	Not applicable
Iron gluconate (Ferelecit)	125 mg	Not applicable	Not applicable
Iron isomaltoside 1000 (Monofer)	≤ 200 mg	≤ 1000 mg not exceeding 20 mg iron/kg	1000–2000 mg ~ 1 h
			0–10 mg iron/kg ~ 30 min
			11–20 mg iron/kg ~ 60 min
Iron carboxymaltose (Ferinject)	≤ 200 mg	≤ 1000 mg not exceeding 15 mg iron/kg	Not applicable
Feraheme (ferumoxytol)	= 510 mg	510 mg	Not applicable

^aAccelerated dose infusion regime used by the author and several other units—Sinha S, Chiu D, Peebles G, Fenwick S, Bhandari S, Kalra P. Accelerated total dose infusion of low-molecular-weight iron dextran is safe and efficacious in chronic kidney disease patients. Quarterly Journal of Medicine, Advanced access published 18 October 2010